Institute for Immunologic Intervention (3i)   

The Institute for Immunologic Intervention at the CDI investigates T cell development in the thymus and T cell immune responses in peripheral tissues.

3i’s Mission

The Hackensack Meridian Health (HMH) Center for Discovery and Innovation (CDI) established the Institute for Immunologic Intervention (3i) with the goal of advancing research in immunology to combat infections, cancer, and inflammatory diseases by enhancing the human immune system's responses. Comprising a team of expert scientists, including basic researchers, physician-scientists, and clinicians, the 3i focuses on understanding fundamental mechanisms of infectious immunity, tumor immunity, alloimmunity, and autoimmunity in clinical contexts. In close clinical and translational research partnerships with the HMH John Theurer Cancer Center and the Georgetown Lombardi Comprehensive Cancer Center (LCCC), which collectively form one of the national NCI-designated comprehensive cancer centers the 3i aims to apply this knowledge to improve cancer immunotherapy, interventions for autoimmune and alloimmune conditions, and infection prevention. The scientists at 3i cover diverse fields such as cancer immunology, immunotherapy, T cell biology, genetics, and microbiome influence on antitumor immunosurveillance.

Physician scientists at Hackensack Meridian Health

Steven A Lee-Kong, M.D.
Colon and Rectal Surgery

Howard M Ross, M.D.
Colon and Rectal Surgery

Martin E Gutierrez, M.D.
GI and Thoracic Medical Oncology

David Siegel, M.D.
Multiple Myeloma, AL Amyloidosis

Lombardi Comprehensive Cancer Center - Based Faculty Members

Samir Khleif, M.D.
Translational Tumor Immunology

Louis Weiner, M.D.
Medical Oncology, Gastrointestinal Cancers

Michael Atkins, M.D.
Anti-angiogenic Therapy, Hematology, Immunotherapy, Kidney Cancer

Alejandro Villagra, Ph.D.
Tumor Microenvironment, Epigenetics, Tumor Immunology

Ben Weinberg, M.D. 
Gastrointestinal Medical Oncology, Hematology Oncology

Joyce Slingerland, M.D., Ph.D.
Cancer Host Interactions, Breast Cancer

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