Institute for Immunologic Intervention (3i)   

The Institute for Immunologic Intervention at the CDI investigates T cell development in the thymus and T cell immune responses in peripheral tissues.

3i’s Mission

The Institute is dedicated to advancing the understanding of T cell development, immunity to infections, tumor immunity, alloimmunity, and autoimmunity. By fostering collaborations with the CDI, John Theurer Cancer Center, and the Georgetown Lombardi Comprehensive Cancer Center, our institute strives to apply this knowledge towards innovative strategies that enhance the effectiveness of cancer immunotherapy, interventions for autoimmune and alloimmune conditions, and the prevention of infections.

Institute for Immunologic Intervention (3i)

3i's Team

Binfeng Lu, Ph.D.
Director, 3i
Cancer Immunology and immunotherapy, Inflammatory Biology
binfeng.lu@hmh-cdi.org

Yi Zhang, M.D., Ph.D.
(CAR) T cell biology, Tumor immunity and Alloimmunity
yi.zhang@hmh-cdi.org

Hai-Hui (Howard) Xue, M.D., Ph.D.
T cell Biology, Tumor Immunity
haihui.xue@hmh-cdi.org

Johannes Zakrzewski, M.D.
Cancer Immunotherapy and Immunosurveillance
Johannes.Zakrzewski@hmh-cdi.org

Rachel Rosenstein, M.D., Ph.D.
Inflammatory and Fibrotic Diseases
rachel.rosenstein@hmhn.org

Sivia Lapidus, M.D., M.D.
Pediatric Rheumatic Conditions and Autoinflammatory Disorders
sivia.lapidus@hmhn.org

Jigar V. Desai, Ph.D.
Innate Immunity, Fungal Infections
jigarkumar.desai@hmh-cdi.org

Physician scientists at Hackensack Meridian Health

Steven A Lee-Kong, M.D.
Colon and Rectal Surgery

Howard M Ross, M.D.
Colon and Rectal Surgery

Martin E Gutierrez, M.D.
GI and Thoracic Medical Oncology

David Siegel, M.D.
Multiple Myeloma, AL Amyloidosis

Lombardi Comprehensive Cancer Center - Based Faculty Members

Samir Khleif, M.D.
Translational Tumor Immunology

Louis Weiner, M.D.
Medical Oncology, Gastrointestinal Cancers

Michael Atkins, M.D.
Anti-angiogenic Therapy, Hematology, Immunotherapy, Kidney Cancer

Alejandro Villagra, Ph.D.
Tumor Microenvironment, Epigenetics, Tumor Immunology

Ben Weinberg, M.D. 
Gastrointestinal Medical Oncology, Hematology Oncology

Joyce Slingerland, M.D., Ph.D.
Cancer Host Interactions, Breast Cancer

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